Heredity is the number one risk factor for venous disease. If both your parents had varicose veins, you have an 89% chance of developing them. Next to heredity is gender. Women, especially those that have had multiple pregnancies, are three times more likely than men to develop venous disorders. Additionally, professions that require long periods of inactivity, whether sitting or standing, increase one's risk for venous disease. Age is also a risk factor. While older people are at a higher risk for venous disease, it can start as early as childhood.